Calculate the Sigma value for a method with total allowable error 8%, bias 0.9%, and CV 2%.

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Study for the Bishop Clinical Chemistry Test. Engage with flashcards and multiple choice questions with hints and explanations to prepare thoroughly for your exam!

Multiple Choice

Calculate the Sigma value for a method with total allowable error 8%, bias 0.9%, and CV 2%.

Explanation:
Sigma value indicates how many standard deviations of total error the method can tolerate after accounting for bias and imprecision. Use the formula Sigma = (TEa − |Bias|) / CV. Here TEa is 8%, bias is 0.9%, and CV is 2%. Subtracting the bias from TEa gives 7.1%. Dividing by CV yields 7.1 / 2 = 3.55, which rounds to 3.6. So the Sigma value is 3.6.

Sigma value indicates how many standard deviations of total error the method can tolerate after accounting for bias and imprecision. Use the formula Sigma = (TEa − |Bias|) / CV. Here TEa is 8%, bias is 0.9%, and CV is 2%. Subtracting the bias from TEa gives 7.1%. Dividing by CV yields 7.1 / 2 = 3.55, which rounds to 3.6. So the Sigma value is 3.6.

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