Hb E is most prevalent in which region?

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Study for the Bishop Clinical Chemistry Test. Engage with flashcards and multiple choice questions with hints and explanations to prepare thoroughly for your exam!

Multiple Choice

Hb E is most prevalent in which region?

Explanation:
Hb E is a beta-globin variant that is highly common in Southeast Asia due to historical malaria-driven selection. The mutation raises its frequency specifically in populations of that region, making carriers relatively common there. In contrast, the Mediterranean, Indian subcontinent, and Northern Europe have much lower frequencies of Hb E. So, the region with the highest prevalence is Southeast Asia.

Hb E is a beta-globin variant that is highly common in Southeast Asia due to historical malaria-driven selection. The mutation raises its frequency specifically in populations of that region, making carriers relatively common there. In contrast, the Mediterranean, Indian subcontinent, and Northern Europe have much lower frequencies of Hb E. So, the region with the highest prevalence is Southeast Asia.

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