In the context of OGTT timing, which combination of measurements is described by the 2012 ADA guidelines?

In the context of OGTT timing, which combination of measurements is described by the 2012 ADA guidelines?

• A. Fasting, 1 hour, and 2 hours
• B. Fasting, 60 minutes, and 120 minutes
• C. 30, 60, 90, and 120 minutes
• D. Fasting, 30, 60, 90, and 120 minutes

Answer: (A)

The main idea being tested is which time points are used to sample glucose during the oral glucose tolerance test according to the 2012 ADA guidelines. After a standardized glucose load, glucose is measured at fasting, then at one hour, and again at two hours. The one-hour measurement adds sensitivity by capturing early post-load glucose handling that may not be evident at the fasting or two-hour marks, while the two-hour value remains the key datum for assessing whether glucose tolerance is normal, impaired, or diabetic. The other timing patterns either omit the one-hour sample or include additional post-load times not described in the 2012 ADA guidelines for the standard diagnostic OGTT, so they don’t fit the guideline-described protocol.

The main idea being tested is which time points are used to sample glucose during the oral glucose tolerance test according to the 2012 ADA guidelines. After a standardized glucose load, glucose is measured at fasting, then at one hour, and again at two hours. The one-hour measurement adds sensitivity by capturing early post-load glucose handling that may not be evident at the fasting or two-hour marks, while the two-hour value remains the key datum for assessing whether glucose tolerance is normal, impaired, or diabetic. The other timing patterns either omit the one-hour sample or include additional post-load times not described in the 2012 ADA guidelines for the standard diagnostic OGTT, so they don’t fit the guideline-described protocol.