The major clinical use for CA-125 is monitoring treatment response of which cancer?

The major clinical use for CA-125 is monitoring treatment response of which cancer?

• A. Ovarian carcinoma
• B. Colorectal cancer
• C. Prostatic cancer
• D. Breast cancer

Answer: (A)

CA-125 is a tumor marker that tracks tumor burden in epithelial ovarian cancer. Its dominant clinical use is to monitor how well treatment is working and to watch for relapse. When therapy reduces the amount of cancer, CA-125 levels usually fall; if the disease progresses or recurs, the levels tend to rise. This monitoring helps guide decisions after surgery and chemotherapy. While CA-125 can be elevated in other conditions, it is not a reliable or standard marker for colorectal, prostate, or breast cancers, where it does not consistently reflect disease status.

CA-125 is a tumor marker that tracks tumor burden in epithelial ovarian cancer. Its dominant clinical use is to monitor how well treatment is working and to watch for relapse. When therapy reduces the amount of cancer, CA-125 levels usually fall; if the disease progresses or recurs, the levels tend to rise. This monitoring helps guide decisions after surgery and chemotherapy. While CA-125 can be elevated in other conditions, it is not a reliable or standard marker for colorectal, prostate, or breast cancers, where it does not consistently reflect disease status.