Which ketone body is primarily detected by the nitroprusside urine test?

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Multiple Choice

Which ketone body is primarily detected by the nitroprusside urine test?

Explanation:
The test detects acetoacetate as the ketone it reacts with most reliably under alkaline conditions to form a colored product with nitroprusside. Acetone can give a weak reaction, but 3-hydroxybutyrate does not react with nitroprusside, so it is not detected by this test. Therefore, the nitroprusside urine test is best described as primarily detecting acetoacetate.

The test detects acetoacetate as the ketone it reacts with most reliably under alkaline conditions to form a colored product with nitroprusside. Acetone can give a weak reaction, but 3-hydroxybutyrate does not react with nitroprusside, so it is not detected by this test. Therefore, the nitroprusside urine test is best described as primarily detecting acetoacetate.

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